Observational Survival Analysis, Epithelial Ovarian Carcinoma Patients
Summary
The National Institutes of Health registered an observational survival analysis study (NCT07540403) evaluating outcomes in epithelial ovarian carcinoma patients with unfavorable prognosis. The study aims to improve patient categorization and management by analyzing survival in recurrent disease patients. Conditions studied include ovarian cancer.
What changed
The NIH added a new clinical trial registry entry for an observational survival analysis study in patients with recurrent epithelial ovarian carcinoma and unfavorable prognosis. The study will evaluate patient characteristics, disease stage, and tumor genetic/molecular profiles to improve categorization and management.
Healthcare providers and clinical investigators involved in ovarian cancer research may reference this registry entry for awareness of ongoing survival analysis studies. The study registration has no direct compliance implications for external parties.
Archived snapshot
Apr 21, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Survival Analysis in patiEnts With Bad Prognosis Epithelial Ovarian CArcinoma
Observational NCT07540403 Kind: OBSERVATIONAL Apr 20, 2026
Abstract
Ovarian carcinoma is the most lethal gynecological malignancy. Epithelial ovarian carcinoma is the gynecological malignancy with the highest mortality rate. The prognosis of patients with recurrent disease is highly heterogeneous and is typically poor in cases of ovarian carcinoma with a progression-free survival (PFS) ≤ 6 months, for which therapeutic options are limited. However, it has been shown that patients with a PFS ≤ 6 months may not respond effectively to further treatments, whereas, conversely, patients with a PFS > 6 months could still benefit from them.
The classification of patients with recurrent disease has undergone continuous evolution over time. Essential factors to consider include patient characteristics, disease stage, and the precise genetic and molecular profile of the tumor. This study aims to evaluate survival in patients experiencing recurrence of epithelial ovarian carcinoma with an unfavorable prognosis, with the objective of improving patient categorization and management.
Conditions: Ovarian Cancer
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