Autoimmune Hyperthyroidism in Prepubertal Children, NCT07544290
Summary
A multicenter retrospective observational study (NCT07544290) registered on ClinicalTrials.gov will assess clinical, biochemical, and auxological characteristics at diagnosis and during follow-up in Caucasian pediatric patients diagnosed with autoimmune hyperthyroidism before puberty. The study will compare prepubertal patients with a control group of post-pubertal patients with Graves' disease to identify age-dependent clinical patterns, therapeutic response, and growth-related outcomes. The study aims to support more tailored management strategies in pediatric populations.
“These prepubertal patients will be compared with a control group of post-pubertal patients with Graves' disease.”
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What changed
The study record for NCT07544290 documents a new multicenter retrospective observational study registered with ClinicalTrials.gov, examining autoimmune hyperthyroidism in prepubertal children. The study will collect clinical, biochemical, and auxological data at diagnosis and follow-up, comparing prepubertal patients with post-pubertal controls to identify age-dependent patterns and prognostic indicators. Healthcare institutions and clinical investigators participating in or referring patients to this study should ensure alignment with their IRB-approved protocols and confirm accuracy of enrollment data in the ClinicalTrials.gov record.
Scheduled event
- Date
- 2026-04-22
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Autoimmune Hyperthyroidism in Prepubertal Children
Observational NCT07544290 Kind: OBSERVATIONAL Apr 22, 2026
Abstract
The investigators propose a multicenter retrospective study to assess clinical, biochemical, and auxological characteristics at diagnosis and during follow-up in a cohort of Caucasian pediatric patients diagnosed with autoimmune hyperthyroidism before puberty. These prepubertal patients will be compared with a control group of post-pubertal patients with Graves' disease.
This study aims to enhance the understanding of autoimmune hyperthyroidism in prepubertal patients by providing a detailed evaluation of disease onset, therapeutic response, and growth-related outcomes. The inclusion of a carefully matched post-pubertal control group will allow for robust comparative analysis and identification of age-dependent clinical patterns and prognostic indicators, ultimately supporting more tailored and effective management strategies in pediatric populations at this particular age.
Conditions: Autoimmune Hyperthyroidism, Children
Interventions: restrospective observational study
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