Multi-Omics Analysis of Lens Zonule Relaxation in PACG Pathogenesis
Summary
NIH registered observational clinical study NCT07539675 on ClinicalTrials.gov examining differential molecular expression in Primary Angle-Closure Glaucoma patients with zonular laxity compared to those without and controls. The study involves no experimental interventions and seeks to construct a mechanistic network from identified molecules.
What changed
NIH registered a new observational clinical study (NCT07539675) on ClinicalTrials.gov. The study aims to identify differentially expressed molecules in Primary Angle-Closure Glaucoma patients with zonular laxity compared to those without and control groups.
Affected parties include healthcare institutions and clinical researchers studying glaucoma pathogenesis. The study registration has no compliance obligations and does not create regulatory requirements for any party.
Archived snapshot
Apr 20, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
The Multi-Omics Analysis of Lens Zonule Relaxation in The PACG Pathogenesis
Observational NCT07539675 Kind: OBSERVATIONAL Apr 20, 2026
Abstract
Compared with primary angle-closure glaucoma (PACG) patients without zonular laxity and the control group, there are differentially expressed molecules in PACG patients with zonular laxity, and a potential mechanistic network can be constructed therefrom.
Conditions: Primary Angle-Closure Glaucoma
Interventions: No Additional Experimental Intervention
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