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Routine Notice Added Final

No New Measles Cases Since Friday, Outbreak Total Stays 997

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Summary

South Carolina DPH reports no new measles cases since Friday's announcement of an isolated Saluda County case. The Upstate outbreak total remains at 997 cases. Forty-one individuals are currently in quarantine related to Saluda County exposure, with quarantine ending May 9. If no new outbreak-related cases are reported, the outbreak will be declared over on April 26.

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What changed

This is a routine public health status update from South Carolina DPH. No new cases of measles have been reported since Friday's announcement of an isolated case in Saluda County unrelated to the ongoing Upstate outbreak. The Upstate outbreak count remains at 997 cases.

For affected parties and healthcare providers, no new compliance obligations or actions are required. The Saluda County quarantine involves 41 individuals and runs through May 9. If no new cases emerge, the 42-day observation period (double the 21-day measles incubation period) will conclude on April 26, allowing the outbreak to be formally declared ended.

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Apr 22, 2026

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TUESDAY MEASLES UPDATE: DPH Reports No New Measles Cases Since Friday, Outbreak Total Remains 997

FOR IMMEDIATE RELEASE:
Apr. 21, 2026

COLUMBIA, S.C. ― Today, the South Carolina Department of Public Health (DPH) is again reporting no new cases of measles in the state since Friday's announcement of an isolated Midlands case in Saluda County. The number of cases related to the Upstate outbreak remains at 997.

There currently is no one in isolation, and 41 are in quarantine related to the Saluda County exposure. The last day of the Saluda County quarantine is May 9.

If no new outbreak-related cases are reported, the last day of the outbreak will be April 26.

A media briefing will be held tomorrow, Wednesday, April 22, at 1 p.m. Barring any further cases, another update will be issued Monday, April 27.

If a new case is reported, DPH will immediately notify the media and resume briefings and updates as appropriate.

A period of 42 days with no new cases is required to declare an end to a measles outbreak. This is double the number of days for an incubation period (21 days) and a clear indicator of a broken transmission chain.

Vaccination continues to be the best way to prevent measles and stop this outbreak. Vaccines are available at many primary care provider offices and pharmacies, as well as DPH Health Departments.

To stay up-to-date on the latest measles outbreak information, visit our dedicated webpage here. For additional data related to the outbreak, visit our Measles Dashboard.

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- ## TUESDAY MEASLES UPDATE: DPH Reports No New Measles Cases Since Friday, Outbreak Total Remains 997

FOR IMMEDIATE RELEASE:
Apr. 21, 2026

COLUMBIA, S.C. ― Today, the South Carolina Department of Public Health (DPH) is again reporting no new cases of measles in the state since Friday's announcement of an isolated Midlands case in Saluda County. The number of cases related to the Upstate outbreak remains at 997.

Read Full Article

FOR IMMEDIATE RELEASE:
Apr. 21, 2026

COLUMBIA, S.C. – Twice a year, in April and October, the U.S. Drug Enforcement Agency (DEA) partners with local law enforcement and other community organizations to host National Prescription Drug Take Back Days. The South Carolina Department of Public Health (DPH) encourages residents to participate in the upcoming National Prescription Drug Take Back Day on Saturday, April 25, by cleaning out and properly disposing of unused or expired medications.

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FOR IMMEDIATE RELEASE:
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- ## DPH Announces Measles Case in Midlands, Unrelated to Upstate Outbreak

FOR IMMEDIATE RELEASE:
Apr. 17, 2026

COLUMBIA, S.C. — The South Carolina Department of Public Health (DPH) has confirmed a case of measles in an adult Saluda County resident. Upon investigation, the case is determined to be the result of international travel and is not related to the Upstate outbreak.

Read Full Article

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Last updated

Classification

Agency
SC DPH
Published
April 21st, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Public health authorities Healthcare providers
Industry sector
9211 Government & Public Administration
Activity scope
Disease surveillance Outbreak reporting Quarantine monitoring
Geographic scope
US-SC US-SC

Taxonomy

Primary area
Public Health
Operational domain
Compliance
Topics
Healthcare

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