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Adductor Canal Block With Tourniquet for Posterior Knee Pain After Total Knee Arthroplasty

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Summary

NIH registered clinical trial NCT07539467, a randomized study comparing Tourniquet-Assisted Adductor Canal Block (T-ACB) versus Standard Adductor Canal Block (S-ACB) for managing posterior knee pain after total knee arthroplasty. The trial enrolled patients with gonarthrosis and tested whether applying a thigh tourniquet postoperatively alongside the adductor canal block improves pain control at the back of the knee. Results from this Phase 4 trial may inform regional anesthesia protocols for knee replacement recovery.

“The biggest fear for patients undergoing knee replacement surgery is that persistent pain felt at the back of the knee postoperatively.”

NIH , verbatim from source
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What changed

NIH registered a new clinical trial examining whether adding a thigh tourniquet to adductor canal block anesthesia improves posterior knee pain management after total knee replacement surgery. The study compares two intervention groups: Tourniquet-Assisted Adductor Canal Block (T-ACB) versus Standard Adductor Canal Block (S-ACB). This is a Phase 4 randomized trial registered in the ClinicalTrials.gov database.

Healthcare providers and clinical investigators monitoring this trial may be interested in the outcomes for informing regional anesthesia protocols. The trial addresses a documented gap in pain management at the posterior knee, where standard regional anesthesia often provides insufficient coverage for the back of the knee joint.

Archived snapshot

Apr 20, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

"The Effect of Adductor Canal Block Performed With Postoperative Thigh Tourniquet Application on Pain After Total Knee Arthroplasty"

N/A NCT07539467 Kind: NA Apr 20, 2026

Abstract

The biggest fear for patients undergoing knee replacement surgery is that persistent pain felt at the back of the knee postoperatively. While regional anesthesia is generally successful at numbing the front of the knee, managing pain in the posterior (back) area is not always easy. In this study, we tested a new method designed to alleviate pain in the back of the knee and improve patient comfort.

Conditions: Total Knee Arthroplasty for Gonarthrosis

Interventions: Tourniquet-Assisted Adductor Canal Block (T-ACB) grou, Standard Adductor Canal Block (S-ACB)

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Last updated

Classification

Agency
NIH
Published
April 20th, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Healthcare providers Clinical investigators Patients
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trial registration Regional anesthesia research Knee replacement surgery
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Topics
Medical Devices Pharmaceuticals

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