Netrin-1 peptide amphiphiles treat central nervous system injury
Summary
USPTO published patent application US20260092252A1 for Netrin-1 mimetic peptide amphiphiles for treating central nervous system injury. The application covers peptide compositions and methods of use. Inventors include Samuel Isaac Stupp, Cara Stephanie Smith, and Zaida Alvarez Pinto.
What changed
The USPTO published patent application US20260092252A1 for Netrin-1 mimetic peptide amphiphiles, which are self-assembling molecules that mimic the natural netrin-1 protein for therapeutic use. The application covers nanofibers displaying bioactive PAs and methods of treating central nervous system injury using these compositions.
For companies developing CNS therapeutics or peptide-based treatments, this published application represents a potential blocking patent that could affect freedom to operate in this technology space. The filing date was September 30, 2025, with Application No. 19345142. No immediate compliance actions are required, but R&D teams should review for potential IP conflicts.
Archived snapshot
Apr 2, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
NETRIN-1 MIMETIC PEPTIDE AMPHIPHILES
Application US20260092252A1 Kind: A1 Apr 02, 2026
Inventors
Samuel Isaac Stupp, Cara Stephanie Smith, Zaida Alvarez Pinto
Abstract
Provided herein are netrin-1 mimetic peptide amphiphiles (PAs) comprising a netrin-1 mimetic sequence, nanofibers displaying the bioactive PAs, and methods of use thereof. The disclosed PAs may be used in cell culture methods and in methods of treating central nervous system injury.
CPC Classifications
C12N 5/0062 C07K 7/64 C12M 21/08 C12M 25/14 C12N 5/0619 C12N 2533/50
Filing Date
2025-09-30
Application No.
19345142
Named provisions
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