Multi-Scale Interactome Profiling of Membrane Proteins Using Photocatalytic Proximity Labeling
Summary
The USPTO published patent application US20260109733A1, filed on December 9, 2025 (Application No. 19413455), covering photocatalysts for activating multiple photoreactive probes and methods of proximity labeling proteins on a cell surface. The application was submitted by inventors James Wells and Zhi Lin. CPC classifications include C07K 1/13 and G01N 33/582. Patent application publications are informational records and do not constitute a granted patent or enforceable IP rights at this stage.
“Photocatalysts for activating multiple photoreactive probes and methods of proximity labeling proteins on a cell surface using same.”
About this source
USPTO classification C07K covers peptides: short amino-acid chains that form the backbone of antibodies, hormones, vaccines, and increasingly a wider class of therapeutic modalities. Every newly published application in C07K lands in this feed, around 175 a month. Applications publish 18 months after filing, so this feed reveals what antibody engineering groups, vaccine developers, and plant biotech researchers were working on in the prior year and a half. Watch this if you compete in biologics, file freedom-to-operate analyses on antibody drug candidates, scout acquisition targets in vaccine platforms, or track protein-based agricultural biotech filings.
What changed
The USPTO published a new patent application disclosing photocatalytic proximity labeling methods for profiling membrane protein interactions at multiple scales on living cell surfaces. The invention covers photocatalysts that activate multiple photoreactive probes to label proteins within proximity of the photocatalyst, enabling interactome mapping. Patent application publications are informational records — no enforceable IP rights are granted at this stage. Researchers in protein biology, drug discovery, and membrane protein characterization should monitor this application's prosecution for scope and any divisional filings. Competitors in the research tools and membrane protein therapeutics space may wish to review the claims for freedom-to-operate purposes once the application progresses toward grant.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
MULTI-SCALE INTERACTOME PROFILING OF MEMBRANE PROTEINS USING PHOTOCATALYTIC PROXIMITY LABELING
Application US20260109733A1 Kind: A1 Apr 23, 2026
Inventors
James Wells, Zhi Lin
Abstract
Photocatalysts for activating multiple photoreactive probes and methods of proximity labeling proteins on a cell surface using same.
CPC Classifications
C07K 1/13 G01N 33/582
Filing Date
2025-12-09
Application No.
19413455
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Source
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