MAPT Targeting Oligonucleotides for Neurodegenerative Disease Treatment
Summary
USPTO published patent application US20260109982A1 on April 23, 2026, filed September 24, 2025 (application no. 19338285), disclosing novel MAPT targeting sequences and MAPT targeting oligonucleotides for the treatment of neurodegenerative diseases. Four inventors are named: Anastasia Khvorova, Chantal Ferguson, Sarah Davis, and Kathryn Monopoli. The CPC classifications indicate this is a biotechnology/pharmaceutical invention (C12N 15/113, A61P 25/28).
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GovPing monitors USPTO Patent Applications - Biotech (C12N) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 258 changes logged to date.
What changed
USPTO published application US20260109982A1 disclosing MAPT targeting oligonucleotides for neurodegenerative disease treatment, naming four inventors: Anastasia Khvorova, Chantal Ferguson, Sarah Davis, and Kathryn Monopoli. The application (no. 19338285) was filed September 24, 2025 and published April 23, 2026. CPC classifications C12N 15/113 and A61P 25/28 indicate a biotechnology/central nervous system therapeutic invention.
Parties interested in RNAi, antisense, or neurodegenerative disease therapeutics should monitor this application's prosecution for competitive intelligence. A published patent application does not yet confer enforceable IP rights; patentability and claim scope will be determined during examination.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
OLIGONUCLEOTIDES FOR MAPT MODULATION
Application US20260109982A1 Kind: A1 Apr 23, 2026
Inventors
Anastasia Khvorova, Chantal Ferguson, Sarah Davis, Kathryn Monopoli
Abstract
This disclosure relates to novel MAPT targeting sequences. Novel MAPT targeting oligonucleotides for the treatment of neurodegenerative diseases are also provided.
CPC Classifications
C12N 15/113 A61K 31/00 A61K 31/7088 A61P 25/28 C12N 15/64 C12N 2310/14 C12N 2310/315 C12N 2310/321 C12N 2310/345 C12N 2310/351 C12N 2310/52 C12N 2320/32
Filing Date
2025-09-24
Application No.
19338285
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