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LMP-1 Expressing Cells and Methods of Use Thereof - Dana-Farber Cancer Institute

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Summary

Dana-Farber Cancer Institute, Inc. has been granted USPTO Patent US12595285B2 covering immunogenic cells expressing LMP1 and methods of use for cancer treatment and T cell activation. The patent, with 15 claims, names Baochun Zhang, Il-Kyu Choi, and Zhe Wang as inventors, with an application filing date of May 13, 2022.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

This document announces the issuance of US Patent 12595285B2 to Dana-Farber Cancer Institute, covering compositions and methods involving immunogenic cells expressing LMP1 (Latent Membrane Protein 1) for cancer treatment and activating T cells. The patent grants exclusive intellectual property rights to this cancer immunotherapy technology in the United States.

Affected parties including pharmaceutical companies, cancer research institutions, and biotechnology firms developing LMP1-based or related immunotherapy treatments should conduct freedom-to-operate analyses to ensure their research and product development activities do not infringe on the newly granted patent claims. This patent may impact licensing negotiations and collaborative research arrangements involving LMP1 technology.

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Archived snapshot

Apr 7, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

LMP-1 expressing cells and methods of use thereof

Grant US12595285B2 Kind: B2 Apr 07, 2026

Assignee

Dana-Farber Cancer Institute, Inc.

Inventors

Baochun Zhang, Il-Kyu Choi, Zhe Wang

Abstract

The disclosure provides immunogenic cells expressing LMP1, and use thereof in activating T cells and treating cancer. Also provided are methods of producing the immunogenic cells.

CPC Classifications

C07K 14/005 A61K 40/42 A61K 40/13 A61K 35/17

Filing Date

2022-05-13

Application No.

17663344

Claims

15

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Last updated

Classification

Agency
USPTO
Published
April 7th, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12595285B2

Who this affects

Applies to
Pharmaceutical companies Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Cancer immunotherapy research Cell therapy development Biotech product development
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Pharmaceuticals

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