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LILRB2 Antibodies and Uses Thereof - Cancer and Autoimmune Treatment

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Summary

The USPTO granted patent US12596122B2 to The Board of Regents of the University of Texas System covering LILRB2 antibodies and their uses for detecting and treating cancer and autoimmune diseases. The patent names 11 inventors and includes 26 claims. The filing date was January 28, 2021, under application number 17759800.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

The USPTO issued patent US12596122B2 to The Board of Regents of the University of Texas System, granting exclusive intellectual property rights to LILRB2 antibodies for cancer and autoimmune disease applications. The patent includes claims covering the antibody compositions and methods of using them for detection and treatment purposes.

For pharmaceutical and biotechnology companies developing immunotherapies or antibody-based therapeutics, this patent may affect freedom-to-operate considerations. Entities conducting research in the LILRB2/ILT4 space should evaluate potential licensing needs or design-around strategies to avoid infringement on the granted claims.

What to do next

  1. Monitor patent portfolio for freedom-to-operate implications
  2. Review licensing opportunities for LILRB2 antibody technology
  3. Assess competitive landscape for similar antibody therapies

Archived snapshot

Apr 7, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

LILRB2 antibodies and uses thereof

Grant US12596122B2 Kind: B2 Apr 07, 2026

Assignee

THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventors

Zhiqiang An, Ningyan Zhang, Zhiqiang Ku, Chengcheng Zhang, Xiaoye Liu, Heyu Chen, JingJing Xie, Maria Jose Costa, An Song, X. Charlene Liao

Abstract

Provided herein are antibodies binding to LILRB2 and the uses of the antibodies in detecting and treating cancer and autoimmune diseases.

CPC Classifications

A61K 47/6849 A61P 35/00

Filing Date

2021-01-28

Application No.

17759800

Claims

26

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Last updated

Classification

Agency
USPTO
Published
April 7th, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12596122B2

Who this affects

Applies to
Pharmaceutical companies Healthcare providers Investors
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent examination IP licensing Biopharmaceutical research
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Pharmaceuticals

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