Lower Intersecting HIV-Related Stigmas to Facilitate Treatment as Prevention (LIFT), Kyrgyzstan
Summary
NIH registered ClinicalTrials.gov study NCT07541131, a randomized implementation study evaluating the LIFT multilevel intervention to reduce HIV transmission risk among people who inject drugs (PWID) in Kyrgyzstan. The study adapts and pilots peer-led group sessions focused on stigma reduction and HIV prevention efficacy, with participants randomized to intervention or control arms.
What changed
This document registers a new clinical trial on ClinicalTrials.gov. The LIFT (Lower Intersecting HIV-related Stigmas to Facilitate Treatment as Prevention) study will adapt and pilot a stigma reduction intervention with PWID and methadone maintenance treatment clinic staff in Kyrgyzstan. Participants are randomized to receive the peer-led intervention or control.
Healthcare providers and researchers studying HIV prevention or harm reduction in Central Asia may find this study relevant to their programs. The study focuses on addressing intragroup PWID support, navigating HIV services under structural stigma, and reducing abstinence-based stigma at health facilities.
Archived snapshot
Apr 21, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Lower Intersecting HIV-related Stigmas to Facilitate Treatment as Prevention (LIFT)
N/A NCT07541131 Kind: NA Apr 21, 2026
Abstract
The purpose of this study is to reduce HIV transmission risk among people who inject drugs (PWID) through a multilevel intervention known as LIFT. LIFT intervenes to build intragroup PWID support at the community-level to reduce overall drug use and stigma. LIFT also increases efficacy in navigating HIV services in the presence of structural stigma. Additionally, LIFT intervenes on abstinence-based drug use stigma at the health facility-level to improve clinic policy and staff interactions with clients.
This is an implementation study to adapt and pilot a stigma reduction intervention with persons who inject drugs (PWID) in Kyrgyzstan. The intervention includes peer-led group sessions focused on stigma reduction and providing support to increase HIV prevention efficacy. The aim will be to adapt, refine, and pilot the intervention among PWID and methadone maintenance treatment (MMT) clinic staff. Participants will be randomized to the intervention or control arms.
Conditions: Stigma, Social, Drug Abuse Illicit, HIV (Human Immunodeficiency Virus)
Interventions: LIFT for People Who Use Drugs, LIFT for MMT Providers
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