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IL-17 antagonist compositions for treating inflammatory arthritis

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Summary

USPTO granted patent US12594333B2 to Novartis AG covering methods of treating inflammatory arthritis using IL-17 antagonists, specifically IL-17 binding molecules such as secukinumab antibodies. The patent contains 16 claims and covers therapeutic regimens for conditions including psoriatic arthritis.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

USPTO issued patent grant US12594333B2 to Novartis AG for compositions and methods of treating inflammatory arthritis using IL-17 antagonists including secukinumab. The patent covers IL-17 binding molecules and receptor binding molecules as therapeutic agents. The filing date was February 24, 2025, and the grant date is April 7, 2026.

For pharmaceutical companies and healthcare providers, this patent establishes exclusive rights that may affect licensing negotiations, generic drug development timelines, and therapeutic approach selections for inflammatory arthritis patients. Novartis gains 20-year patent protection for these therapeutic regimens in the United States.

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Archived snapshot

Apr 7, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Methods of treating inflammatory arthritis using IL-17 antagonists

Grant US12594333B2 Kind: B2 Apr 07, 2026

Assignee

NOVARTIS AG

Inventors

Shephard Mpofu, Hanno Richards, Karthinathan Thangavelu, Matthias Machacek

Abstract

The disclosure relates to novel regimens for treating an inflammatory arthritis, e.g., psoriatic arthritis, which employ a therapeutically effective amount of an Interleukin-17 (IL-17) antagonist, e.g., IL-17 binding molecule (e.g., IL-17 antibody or antigen binding fragment thereof, e.g., secukinumab) or IL-17 receptor binding molecule (e.g., IL-17 antibody or antigen binding fragment thereof).

CPC Classifications

A61K 39/3955 A61K 2039/505 C07K 2317/76 A61P 17/06 A61P 19/02

Filing Date

2025-02-24

Application No.

19061831

Claims

16

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Last updated

Classification

Agency
USPTO
Published
April 7th, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12594333B2

Who this affects

Applies to
Pharmaceutical companies Healthcare providers Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent examination IP licensing Biopharmaceutical R&D
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Healthcare

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