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HA-Paclitaxel Conjugate Patent for Treatment of Mesothelioma

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Summary

USPTO granted Patent US12605355B2 to Fidia Farmaceutici S.p.A. covering HA-paclitaxel conjugate compositions for loco-regional treatment of malignant mesothelioma. The patent, with 13 claims, covers malignant pleural, pericardial, and peritoneal mesothelioma applications, with priority dating to the April 7, 2021 filing.

“HA-paclitaxel conjugate for use in the loco-regional treatment of the mesothelioma, i.e., the malignant pleural mesothelioma, pericardial mesothelioma and peritoneal mesothelioma, preferably malignant pleural mesothelioma, and relative pharmaceutical compositions are described.”

USPTO , verbatim from source
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What changed

USPTO issued Patent US12605355B2 to Fidia Farmaceutici S.p.A. for an HA-paclitaxel conjugate designed for loco-regional treatment of mesothelioma, including malignant pleural, pericardial, and peritoneal forms. The patent includes 13 claims covering the conjugate composition and associated pharmaceutical formulations.

Fidia Farmaceutici gains exclusive IP rights to this therapeutic application in the United States. Competitors developing similar locoregional paclitaxel-based treatments for mesothelioma should review the claim scope for potential freedom-to-operate considerations. The patent's issuance may affect licensing negotiations and R&D investment decisions in this therapeutic area.

Archived snapshot

Apr 21, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

HA-paclitaxel conjugate for treatment of mesothelioma

Grant US12605355B2 Kind: B2 Apr 21, 2026

Assignee

Fidia Farmaceutici S.p.A.

Inventors

Carlo Pizzocaro, Antonio Rosato

Abstract

HA-paclitaxel conjugate for use in the loco-regional treatment of the mesothelioma, i.e., the malignant pleural mesothelioma, pericardial mesothelioma and peritoneal mesothelioma, preferably malignant pleural mesothelioma, and relative pharmaceutical compositions are described.

CPC Classifications

A61K 31/337 A61K 47/61 A61K 9/0019 A61P 35/00

Filing Date

2021-04-07

Application No.

17916645

Claims

13

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Last updated

Classification

Agency
USPTO
Published
April 21st, 2026
Instrument
Rule
Branch
Executive
Legal weight
Binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Pharmaceutical companies Manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent granting IP rights issuance
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Healthcare

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