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Fusion antibody for presenting antigen-derived T cell epitope

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Summary

USPTO granted Patent US12590156B2 to AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION for a fusion antibody composition designed to deliver viral antigen-derived CD8+ T cell antigen epitopes to target cell cytoplasm for presentation on major histocompatibility complex class I (MHC-I) molecules. The patent contains 22 claims covering the composition and its use in antigen presentation.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

USPTO issued Patent US12590156B2 on March 31, 2026, granting AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION exclusive rights to a fusion antibody technology for delivering CD8+ T cell antigen epitopes to cell cytoplasm. The patent covers a composition comprising the fusion antibody and methods for presenting antigen-derived epitopes on MHC-I molecules. The invention was filed as Application No. 17796788 on February 5, 2021, with 22 claims allowed.

This patent grant does not impose immediate compliance obligations on other entities. Companies developing T cell-based immunotherapies, vaccines, or related fusion antibody technologies should review the patent claims to assess potential licensing needs or freedom-to-operate concerns. The granted patent provides the assignee with enforceable exclusive rights in the US for the claimed fusion antibody compositions and methods.

Archived snapshot

Mar 31, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Fusion antibody for presenting antigen-derived T cell antigen epitope or peptide containing same on cell surface, and composition comprising same

Grant US12590156B2 Kind: B2 Mar 31, 2026

Assignee

AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventors

Yong Sung Kim, Jeong-Ah Kim, Keunok Jung, Seyoung Lee, Min-Jeong Son

Abstract

The present invention relates to: a composition for delivering a viral antigen-derived CD8+ T cell antigen epitope or a peptide comprising same to the cytoplasm of a target cell to thereby present the epitope or peptide to major histocompatibility complex class I (MAC-1), which is an antigen-presenting molecule on the cell surface; a composition comprising same; and a use thereof.

CPC Classifications

A61P 31/00

Filing Date

2021-02-05

Application No.

17796788

Claims

22

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Named provisions

Fusion antibody composition CD8+ T cell antigen epitope delivery MHC-I antigen presentation

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Last updated

Classification

Agency
USPTO
Published
March 31st, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12590156B2

Who this affects

Applies to
Pharmaceutical companies Healthcare providers Medical device makers
Industry sector
3254.1 Biotechnology 3254 Pharmaceutical Manufacturing 6211 Healthcare Providers
Activity scope
Patent Licensing Biotechnology Research Immunotherapy Development
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Biotechnology Pharmaceuticals Healthcare

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