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Treatment of cachexia using fibroblast cells and products thereof

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Summary

USPTO granted patent US12589119B2 to Fibrobiologics, Inc. covering methods and compositions for treating cachexia using immune-modulating fibroblasts. Inventors Pete O'Heeron and Thomas Ichim disclosed compositions including immune-modulating fibroblasts for treatment, amelioration, or prevention of cachexia or inflammation related to cachexia. The patent contains 12 claims.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

USPTO issued patent grant US12589119B2 to Fibrobiologics, Inc. for methods of treating cachexia using immune-modulating fibroblast compositions. The patent, with application number 17309177 filed November 4, 2019, contains 12 claims covering the therapeutic compositions and methods of administration. CPC classifications include A61K 35/33, A61P 21/00, and A61P 1/14.

This is a routine patent grant notice providing intellectual property rights rather than regulatory obligations. No compliance actions, deadlines, or penalties are associated with this document. Entities developing similar fibroblast-based cachexia treatments should review the patent claims to assess potential infringement considerations.

Archived snapshot

Mar 31, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Treatment of cachexia using fibroblast cells and products thereof

Grant US12589119B2 Kind: B2 Mar 31, 2026

Assignee

FIBROBIOLOGICS, INC.

Inventors

Pete O'Heeron, Thomas Ichim

Abstract

Disclosed are methods and compositions related to treatment, amelioration or prevention of cachexia or inflammation related to cachexia in a subject. As disclosed, cachexia or inflammation related to cachexia can be treated, ameliorated or prevented by the administration of an effective amount of a composition including immune-modulating fibroblasts to the subject.

CPC Classifications

A61K 35/33 A61P 21/00 A61P 1/14

Filing Date

2019-11-04

Application No.

17309177

Claims

12

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Named provisions

Methods and compositions related to treatment of cachexia Administration of immune-modulating fibroblasts

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Last updated

Classification

Agency
USPTO
Published
March 31st, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US12589119B2

Who this affects

Applies to
Healthcare providers Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Biotechnology Pharmaceutical Manufacturing
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Healthcare Intellectual Property

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