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JIA Toolbox Feasibility Study, 25 Children, NCT07543575

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Summary

NIH registered a feasibility study (NCT07543575) for the 'JIA Toolbox' — three medical device prototypes (heating prototype, physio tool, communication tool) designed to improve independence and functional ability in children aged 7-16 with Juvenile Idiopathic Arthritis. The study will recruit 25 children and their parent/guardian from Sheffield Children's NHS Foundation Trust over a 3-month feasibility period across six work packages covering design, production, recruitment, intervention, and data analysis. This follows a 2021 proof-of-concept study with 10 participants that established prototypes addressed an unmet need.

“The feasibility study aims to test the effectiveness and viability of 'JIA Toolbox' in improving CYP with JIA's independence, functional ability, and therefore overall condition management.”

NIH , verbatim from source
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GovPing monitors ClinicalTrials.gov Studies for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 588 changes logged to date.

What changed

NIH registered a new clinical trial (NCT07543575) on ClinicalTrials.gov describing a feasibility study of the 'JIA Toolbox' — three prototypes (heating, physio, and communication tools) for children with Juvenile Idiopathic Arthritis. The study will enroll 25 participants aged 7-16 from Sheffield Children's NHS Foundation Trust, running a 3-month feasibility intervention across six structured work packages.

Affected parties include pediatric rheumatology research sites, medical device developers in the pediatric assistive devices space, and NHS-affiliated clinical investigators conducting JIA intervention research. The trial builds on a 2021 proof-of-concept (10 CYP over 9 weeks) and aims to generate an evidence base for the prototypes' effectiveness and viability.

Archived snapshot

Apr 22, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

JIA Toolbox Feasibility Study

N/A NCT07543575 Kind: NA Apr 22, 2026

Abstract

Juvenile Idiopathic Arthritis (JIA) is a long-term rheumatic disease affecting approximately 15,000 children and young people (CYP) in the UK. JIA causes ongoing/long-term joint inflammation, pain, and stiffness, making everyday activities difficult. JIA has been shown to impact physical, social, emotional, and educational development. CYP with JIA find current product aids difficult to use, stigmatising and patronising.

This project follows on from a previous successful proof-of-concept study in 2021, involving initial testing on 10 CYP over 9 weeks. These results established that the prototypes addressed an unmet need and worked well. We now propose a feasibility study involving 25 children using the prototypes over 3 months to assess their suitability and further develop an evidence base. The prototypes - 'JIA Toolbox'- consist of three prototypes that collectively aim to improve CYP's independence and functional ability.

This project consists of 6 Work Packages (WP):

WP1: Post application and pre-award start WP2: Design and development WP3: Production of final prototypes WP4: Recruitment of participants WP5: Feasibility intervention period WP6: Data analysis and dissemination

The feasibility study aims to test the effectiveness and viability of 'JIA Toolbox' in improving CYP with JIA's independence, functional ability, and therefore overall condition management. The study will involve recruiting 25 CYP with JIA aged 7-16 and their parent/guardian from Sheffield Chi...

Conditions: Juvenile Idiopahtic Arthritis

Interventions: Heating prototype (Prototype 1), Physio tool (Prototype 2), Communication tool (Prototype 3)

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Last updated

Classification

Agency
NIH
Published
April 22nd, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
NCT07543575

Who this affects

Applies to
Healthcare providers Medical device makers Clinical investigators
Industry sector
3345 Medical Device Manufacturing
Activity scope
Medical device prototyping Clinical feasibility study Pediatric device testing
Geographic scope
United States US

Taxonomy

Primary area
Medical Devices
Operational domain
Clinical Operations
Compliance frameworks
GxP
Topics
Healthcare Pharmaceuticals

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