Guardant Health European Patent for Patient Survival Prediction via Joint Modeling of Longitudinal and Time-to-Event Data
Summary
The EPO published European patent application EP4649489A1 on April 15, 2026, filed by Guardant Health, Inc. The application covers methods for joint modeling of longitudinal biomarker measurements and time-to-event data to predict patient survival outcomes. Inventors include Christopher Pretz, Aaron Isaac Hardin, and Amar Das. The application is classified under IPC categories G16B and G16H (health informatics) and designates multiple European states including AT, BE, DE, ES, FR, GB, IT, NL, and SE. As an A1 publication, this is the administrative announcement of the patent application's filing and search report — not a granted patent.
About this source
GovPing monitors EPO Patent Bulletin - Health Informatics (G16H) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 69 changes logged to date.
What changed
The EPO published European patent application EP4649489A1 for Guardant Health, Inc., covering computational methods that jointly model longitudinal biomarker data with time-to-event outcomes to predict patient survival. The application names three inventors and is classified under health informatics IPC categories G16B and G16H. As an A1 publication, the document announces the application's filing and search report but does not represent a granted patent — examination has not yet been completed.
Affected parties include biotechnology and diagnostics companies developing predictive models for patient outcomes, as well as entities operating in the liquid biopsy or cancer diagnostics space. No immediate compliance obligations arise from this publication. However, firms developing similar joint-modeling approaches for survival prediction in oncology or chronic disease may wish to review the application's claims upon grant to assess potential freedom-to-operate considerations.
Archived snapshot
Apr 24, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
JOINT MODELING OF LONGITUDINAL AND TIME-TO-EVENT DATA TO PREDICT PATIENT SURVIVAL
Publication EP4649489A1 Kind: A1 Apr 15, 2026
Applicants
Guardant Health, Inc.
Inventors
PRETZ, Christopher, HARDIN, Aaron Isaac, DAS, Amar
IPC Classifications
G16B 20/00 20190101AFI20240719BHEP G16B 40/00 20190101ALI20240719BHEP G16H 50/20 20180101ALI20240719BHEP G16H 50/30 20180101ALI20240719BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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