EP3463576A1 Phenolic TRPV1 Agonist Prodrugs for Local Anesthesia
Summary
The European Patent Office published application EP3463576A1 on April 15, 2026, covering prodrugs of phenolic TRPV1 agonists combined with local anesthetics and vasoconstrictors for improved local anesthesia. Applicant Concentric Analgesics, Inc. filed the application with inventors Donovan, John F. and Husfeld, Craig. The application designates 32 European states including Germany, France, the United Kingdom, Italy, Spain, and the Netherlands under IPC classifications A61P 29/00 (analgesics) and A61P 35/00 (antineoplastic agents).
“PRODRUGS OF PHENOLIC TRPV1 AGONISTS IN COMBINATION WITH LOCAL ANESTHETICS AND VASOCONSTRICTORS FOR IMPROVED LOCAL ANESTHESIA”
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GovPing monitors EPO Patent Bulletin - Therapeutics (A61P) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 17 changes logged to date.
What changed
The EPO published patent application EP3463576A1 for prodrugs of phenolic TRPV1 agonists formulated with local anesthetics and vasoconstrictors intended to enhance local anesthesia. The application names Concentric Analgesics, Inc. as applicant and designates 32 European Patent Convention states for potential protection. This publication makes the technical details of the invention publicly available, establishing prior art from the publication date.
Affected parties in the pharmaceutical and analgesic development space should review this publication for freedom-to-operate considerations, particularly companies developing TRPV1-targeted pain therapeutics or long-acting local anesthetic formulations. The publication does not itself grant patent rights but initiates the examination process and creates disclosure obligations for similar inventions under development.
Scheduled event
- Date
- 2026-04-15
Archived snapshot
Apr 22, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
PRODRUGS OF PHENOLIC TRPV1 AGONISTS IN COMBINATION WITH LOCAL ANESTHETICS AND VASOCONSTRICTORS FOR IMPROVED LOCAL ANESTHESIA
Publication EP3463576A1 Kind: A1 Apr 15, 2026
Applicants
Concentric Analgesics, Inc.
Inventors
DONOVAN, John F., HUSFELD, Craig
IPC Classifications
A61P 29/00 20060101AFI20191206BHEP A61P 35/00 20060101ALI20191206BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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