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Superselective Renal Artery Embolization for Renal Angiomyolipoma Observational Study NCT07538908

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Summary

NIH ClinicalTrials.gov has registered a new observational study (NCT07538908) evaluating superselective renal artery embolization as a treatment for renal angiomyolipoma. The prospective study will assess changes in serum creatinine and hemoglobin levels post-procedure, technical success rates, and complication incidence. Enrollment criteria include radiologically confirmed angiomyolipoma based on CT/MRI findings with clinical indications for embolization.

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What changed

NIH has registered a new prospective observational study (NCT07538908) titled 'Superselective Renal Artery Embolization for Renal Angiomyolipoma' on ClinicalTrials.gov. The study will evaluate the efficacy and safety of selective endovascular embolization in treating renal angiomyolipoma through assessment of serum creatinine and hemoglobin level changes, technical success rates, and complications. Inclusion criteria require radiologically confirmed angiomyolipoma via CT and/or MRI with clinical indications for embolization.

Healthcare providers participating in or referring patients for renal angiomyolipoma treatment may wish to be aware of this study as it may inform future treatment protocols. The study's focus on preserving renal function while achieving technical success represents a key endpoint of interest for clinical decision-making in this patient population.

Archived snapshot

Apr 21, 2026

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Superselective Renal Artery Embolization for Renal Angiomyolipoma

Observational NCT07538908 Kind: OBSERVATIONAL Apr 20, 2026

Abstract

To evaluate the efficacy and safety of selective endovascular embolization in the treatment of renal angiomyolipoma (AML). Materials and Methods: A prospective analysis will be conducted on patients who undergo transcatheter renal artery embolization for renal angiomyolipoma. Inclusion criteria will be radiologically confirmed angiomyolipoma based on CT and/or MRI findings and the presence of clinical indications for embolization. The primary outcomes will include the assessment of changes in serum creatinine and hemoglobin levels post-procedure, technical success rates, and the incidence of any complications. Expected Results: Data on patient demographics, tumor characteristics, and procedural outcomes will be collected and analyzed. Conclusion: This study aims to determine whether selective endovascular embolization is a safe and effective treatment modality for renal angiomyolipoma, with the expectation of demonstrating a high rate of technical success while preserving renal function.

Conditions: Selective Endovascular Embolization of Kidney Artery

Interventions: Selective endovascular embolization of kidney artery

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Last updated

Classification

Agency
NIH
Published
April 20th, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Healthcare providers Clinical investigators
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trial registration Endovascular procedure evaluation
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Topics
Medical Devices Pharmaceuticals

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