Diaphragmatic Breathing vs Incentive Spirometry for GERD - NCT07544433
ClinicalTrials.gov Studies
Summary
Clinical trial NCT07544433 registered on ClinicalTrials.gov evaluates two non-invasive respiratory interventions—diaphragmatic breathing exercise (DBE) and volume-oriented incentive spirometry (VIS)—against standard care in patients with gastroesophageal reflux disease (GERD). The 6-week randomized controlled trial will measure outcomes including GERD symptom scores (GERDQ), esophageal acid exposure time, lower esophageal sphincter pressure, and health-related quality of life (GERD-HRQL). Three groups of participants will undergo baseline and post-intervention assessments with daily symptom and adherence diaries.
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What changed
A new clinical trial registration (NCT07544433) has been published on ClinicalTrials.gov, sponsored by NIH, studying the effects of diaphragm-oriented breathing training on gastroesophageal reflux disease. The randomized controlled trial will enroll participants assigned to one of three groups: diaphragmatic breathing exercise, volume-oriented incentive spirometry, or usual care control.
Healthcare providers and clinical investigators involved in GERD management or respiratory therapy research should note this trial's inclusion of both symptom-based (GERDQ) and quality-of-life (GERD-HRQL) endpoints, as well as esophageal function testing. The protocol may be relevant to those recruiting patients for gastroesophageal research or evaluating non-pharmacological GERD interventions.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Diaphragmatic Training on GERD
N/A NCT07544433 Kind: NA Apr 22, 2026
Abstract
he goal of this clinical trial is to evaluate the effects of diaphragm-oriented breathing training on patients with gastroesophageal reflux disease (GERD). This study will compare two non-invasive respiratory interventions-diaphragmatic breathing exercise (DBE) and volume-oriented incentive spirometry (VIS)-in terms of their impact on esophageal function and health-related quality of life.The main questions it aims to answer are:Does DBE or VIS improve GERD symptoms as measured by the GERD Questionnaire (GERDQ)?Do these interventions reduce esophageal acid exposure time and the number of reflux episodes?Do these interventions improve lower esophageal sphincter (LES) pressure and esophageal motility?Do these interventions improve GERD-related quality of life as measured by the GERD-HRQL questionnaire?Researchers will compare three groups: DBE, VIS, and a control group receiving standard care, to determine whether diaphragm-oriented breathing training provides additional benefits over usual management.Participants will:Be randomly assigned to one of three groups (DBE, VIS, or control)Perform the assigned intervention for 6 weeksUndergo baseline and post-intervention assessments, including symptom questionnaires and esophageal function testing Record symptoms and adherence in a daily diary
Conditions: GERD, Diaphragmatic Training
Interventions: Volume-oriented incentive spirometry, Diaphragmatic breathing exercise, Usual Care Group
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