Cationic Lipid Compositions for Tissue-Specific Delivery
Summary
USPTO published patent application US20260108623A1 filed by Shikha Mishra and Xavier De Mollerat Du Jeu on December 10, 2025. The application covers cationic lipid compositions for delivering bioactive agents—therapeutic or diagnostic—specifically to spleen tissue, using lipid aggregates that do not require biomolecular targeting. The compositions include cationic lipids, helper lipids, and a biostability enhancing agent.
“Provided herein are, inter alia, compositions and methods useful for the in vivo delivery of bioactive agents (e.g., therapeutic or diagnostic agents).”
About this source
GovPing monitors USPTO Patent Applications - Therapeutics (A61P) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 219 changes logged to date.
What changed
USPTO published patent application US20260108623A1 for cationic lipid compositions designed for tissue-specific delivery of bioactive agents to spleen tissue. The compositions consist of cationic lipids, helper lipids, and a biostability enhancing agent forming lipid aggregates with the bioactive agent for systemic delivery. Patent applicants are Shikha Mishra and Xavier De Mollerat Du Jeu; filing date was December 10, 2025 with application number 19415525.
Pharmaceutical and biotechnology companies developing lipid-based drug delivery systems should monitor this published application for freedom-to-operate considerations, particularly those working on spleen-targeted therapeutics or nucleic acid delivery platforms. The publication represents USPTO's formal acknowledgment of the application's filing; examination proceedings will determine whether claims are allowed.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
CATIONIC LIPID COMPOSITIONS FOR TISSUE-SPECIFIC DELIVERY
Application US20260108623A1 Kind: A1 Apr 23, 2026
Inventors
Shikha Mishra, Xavier De Mollerat Du Jeu
Abstract
Provided herein are, inter alia, compositions and methods useful for the in vivo delivery of bioactive agents (e.g., therapeutic or diagnostic agents). The compositions provided herein include cationic lipids, helper lipids and a biostability enhancing agent, which together form a lipid aggregate with the bioactive agent and allow for the systemic delivery of the bioactive agent to, for example, spleen tissue without the requirement for biomolecular targeting.
CPC Classifications
A61K 47/6917 A61K 9/0019 A61K 9/1272 A61K 31/7105 A61K 31/713 A61K 47/541 A61K 47/549 A61P 11/00 C12N 9/22 C12N 15/88
Filing Date
2025-12-10
Application No.
19415525
Related changes
Get daily alerts for USPTO Patent Applications - Therapeutics (A61P)
Daily digest delivered to your inbox.
Free. Unsubscribe anytime.
Source
About this page
Every important government, regulator, and court update from around the world. One place. Real-time. Free. Our mission
Source document text, dates, docket IDs, and authority are extracted directly from USPTO.
The summary, classification, recommended actions, deadlines, and penalty information are AI-generated from the original text and may contain errors. Always verify against the source document.
Classification
Who this affects
Taxonomy
Browse Categories
Get alerts for this source
We'll email you when USPTO Patent Applications - Therapeutics (A61P) publishes new changes.
Subscribed!
Optional. Filters your digest to exactly the updates that matter to you.