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Brain State Optimization Methods - Santarnecchi

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Summary

Emiliano Santarnecchi filed patent application US20260112487A1 on June 5, 2023, which published on April 23, 2026, covering methods and apparatus for transitioning a brain from an initial state to a target state using non-invasive stimulation. The application discloses protocols estimated from the brain's structural composition and functional architecture, and also describes using brain information to inform computational general AI agent design. The publication represents new intellectual property in the neurotechnology and AI sectors.

“Methods and apparatus for changing a brain state of a person from an initial brain state to a target brain state are described.”

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GovPing monitors USPTO Patent Applications - Health Informatics (G16H) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 146 changes logged to date.

What changed

USPTO published patent application US20260112487A1 by Emiliano Santarnecchi, covering methods and apparatus for changing brain states from an initial state to a target state using non-invasive brain stimulation. The method includes receiving information characterizing the initial brain state including structural composition and functional architecture, estimating the brain's potential to change states, and determining a non-invasive brain stimulation protocol based on that information.

Researchers and companies developing non-invasive brain stimulation technology should review the application claims for potential freedom-to-operate concerns and licensing opportunities. The broad language covering 'computational general artificial intelligence agents' informed by brain information suggests implications for neurotechnology-adjacent AI development as well.

Archived snapshot

Apr 23, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

SYSTEMS AND METHODS TO MEASURE, PREDICT AND OPTIMIZE BRAIN FUNCTION

Application US20260112487A1 Kind: A1 Apr 23, 2026

Inventors

Emiliano Santarnecchi

Abstract

Methods and apparatus for changing a brain state of a person from an initial brain state to a target brain state are described. The method includes receiving information characterizing the initial brain state, the information including a structural composition and a functional architecture of the brain, estimating based, at least in part, on the received information, a potential for the brain to change from the initial brain state to the target brain state, determining based, at least in part, on the received information and the estimated potential for the brain to change from the initial brain state to the target brain state, a non-invasive brain stimulation protocol, and controlling at least one non-invasive brain stimulation device to stimulate the brain according to the non-invasive brain stimulation protocol. The method also includes using brain information to inform the design of computational general artificial intelligence agents.

CPC Classifications

G16H 50/20 A61B 5/372

Filing Date

2023-06-05

Application No.

18871615

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Last updated

Classification

Agency
USPTO
Published
April 23rd, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260112487A1

Who this affects

Applies to
Medical device makers Manufacturers Researchers
Industry sector
3345 Medical Device Manufacturing
Activity scope
Patent application Brain stimulation technology Medical device research
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Artificial Intelligence

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