BASF SE Patent - Oxadiazole Synthesis Method
Summary
USPTO granted BASF SE patent US12606531B2 on April 21, 2026, covering a process for preparing substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles. The method uses amidoxime compounds reacting with a haloacetic ester in the presence of a base. The patent contains 17 claims with inventors Florian Vogt, Kailaskumar Borate, Bernd Wolf, Christopher Koradin, Roland Goetz, and Harish Shinde.
What changed
USPTO granted BASF SE patent US12606531B2 for a process of preparing substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles via reaction of amidoxime compounds with a haloacetic ester in the presence of a base. The patent contains 17 claims and names six inventors.
Chemical and pharmaceutical manufacturers should review whether the 17 granted claims potentially cover their products or processes. Competitors developing similar compounds or synthesis methods should assess freedom-to-operate and consider whether licensing is needed.
Archived snapshot
Apr 21, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Preparation of substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles
Grant US12606531B2 Kind: B2 Apr 21, 2026
Assignee
BASF SE
Inventors
Florian Vogt, Kailaskumar Borate, Bernd Wolf, Christopher Koradin, Roland Goetz, Harish Shinde
Abstract
The present invention relates to a process for the preparation of substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles of formula (I), which can be obtained through reaction of amidoxime compounds of formula (II) with a haloacetic ester in the presence of a base.
CPC Classifications
C07D 271/06
Filing Date
2021-02-01
Application No.
17795941
Claims
17
Parties
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