IRBM Azole SHP2 Inhibitors Patent EP4345101A1
Summary
The European Patent Office published patent application EP4345101A1, filed by IRBM S.P.A. and C.N.C.C.S. S.c.a.r.l. Collezione Nazionale Dei Composti Chimici e Centro Screening, covering azole derivatives as SHP2 inhibitors for therapeutic use. The application includes claims for treating cancer, immune disorders, and respiratory conditions, with inventors including Alessia Petrochchi, Christian Montalbetti, Romano Di Fabio, Alina Ciammaichella, and Ilaria Rossetti. The publication is designated for all European member states.
About this source
GovPing monitors EPO Patent Bulletin - Organic Chemistry (C07D) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 22 changes logged to date.
What changed
The EPO published patent application EP4345101A1 for azole derivatives serving as SHP2 protein inhibitors. The applicants are IRBM S.P.A. and C.N.C.C.S. S.c.a.r.l. Collezione Nazionale Dei Composti Chimici e Centro Screening, with the invention covering therapeutic applications including oncology indications and immune modulation. SHP2 is a protein tyrosine phosphatase implicated in cancer cell signaling pathways.
Pharmaceutical researchers and drug developers working in oncology or immunology should review the patent claims to assess potential freedom-to-operate implications. Competitors developing SHP2 inhibitors for cancer or autoimmune applications may need to evaluate whether the azole derivative claims conflict with their own research programs.
Archived snapshot
Apr 22, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
AZOLE DERIVATIVES AS SHP2 INHIBITORS
Publication EP4345101A1 Kind: A1 Apr 15, 2026
Applicants
IRBM S.P.A., C.N.C.C.S. S.c.a.r.l. Collezione Nazionale
Dei Composti Chimici e Centro Screening
Inventors
PETROCCHI, Alessia, MONTALBETTI, Christian, DI FABIO, Romano, CIAMMAICHELLA, Alina, ROSSETTI, Ilaria
IPC Classifications
C07D 471/20 20060101AFI20230223BHEP A61K 31/438 20060101ALI20230223BHEP A61P 35/00 20060101ALI20230223BHEP A61P 35/02 20060101ALI20230223BHEP A61P 35/04 20060101ALI20230223BHEP A61P 9/00 20060101ALI20230223BHEP A61P 37/00 20060101ALI20230223BHEP A61P 37/02 20060101ALI20230223BHEP A61P 37/06 20060101ALI20230223BHEP A61P 11/00 20060101ALI20230223BHEP A61P 27/00 20060101ALI20230223BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
Parties
Related changes
Get daily alerts for EPO Patent Bulletin - Organic Chemistry (C07D)
Daily digest delivered to your inbox.
Free. Unsubscribe anytime.
Source
About this page
Every important government, regulator, and court update from around the world. One place. Real-time. Free. Our mission
Source document text, dates, docket IDs, and authority are extracted directly from EPO.
The summary, classification, recommended actions, deadlines, and penalty information are AI-generated from the original text and may contain errors. Always verify against the source document.
Classification
Who this affects
Taxonomy
Browse Categories
Get alerts for this source
We'll email you when EPO Patent Bulletin - Organic Chemistry (C07D) publishes new changes.
Subscribed!
Optional. Filters your digest to exactly the updates that matter to you.