Autologous Fat Grafting for Penile Girth Augmentation
ClinicalTrials.gov Studies
Summary
A clinical trial evaluating autologous fat grafting for penile girth augmentation is registered on ClinicalTrials.gov under NCT07547839. The study will enroll male individuals aged 21-60 with a flaccid mid-shaft penile circumference below 11 cm who are dissatisfied with penile girth, involving extraction of 40-80 mL of fat from the lower abdomen. Researchers will assess clinical success via mean change in penile mid-shaft circumference, use high-resolution ultrasonography at 6 weeks post-operatively to evaluate fat layer survival, and measure patient satisfaction at 3-month follow-up.
“The primary aim of this study is to evaluate the clinical and radiological efficacy and long-term stability of autologous fat grafting as a method for girth augmentation.”
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What changed
This document registers a new clinical trial (NCT07547839) on ClinicalTrials.gov, describing an open-label single-arm study investigating the efficacy and long-term stability of autologous fat grafting for penile girth augmentation. Fat harvested from the lower abdomen (40-80 mL) is washed and injected into the penile dartos layer. Participants meeting eligibility criteria (men 21-60 years, regular coital activity, flaccid mid-shaft circumference under 11 cm) will undergo follow-up at 6 weeks and 3 months.
For the clinical research community, this trial represents a contribution to the evidence base for a cosmetic urology procedure that currently lacks robust long-term data on fat graft survival and patient satisfaction. Clinical investigators and IRB/IEC members reviewing similar investigator-initiated studies should note the inclusion of objective radiological endpoints (ultrasound-measured graft thickness) alongside patient-reported outcome measures, a design feature that may be relevant to peer proposals in aesthetic or reconstructive genital surgery.
Archived snapshot
Apr 24, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Efficacy and Stability of Autologous Fat Grafting for Penile Girth Augmentation
N/A NCT07547839 Kind: NA Apr 23, 2026
Abstract
The primary aim of this study is to evaluate the clinical and radiological efficacy and long-term stability of autologous fat grafting as a method for girth augmentation. The procedure involves extracting approximately 40-80 mL of fat from the patient's lower abdomen. This harvested fat is repeatedly washed , and then injected into the penile dartos layer to enhance penile circumference.
The study will enroll male individuals between 21-60 years old who have regular coital activity, are dissatisfied with their penile girth, and have a flaccid mid-shaft penile circumference of less than 11 cm.
Researchers will measure the clinical success of the procedure by tracking the mean change in penile mid-shaft circumference. Additionally, high-resolution ultrasonography will be used at 6 weeks post-operatively to objectively assess the survival and thickness of the transplanted fat layer. Finally, at a three-month follow-up, patient satisfaction will be evaluated to measure improvements in aesthetic outcomes and functional satisfaction.
Conditions: Penile Girth Augmentation, Fat Graft
Interventions: Autologous Fat Grafting
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