Anti-TIGIT Antibodies Treat Cancers, Viral Infections
Summary
USPTO granted patent US12606619B2 to Huahui Health Ltd. on April 21, 2026. The patent covers human monoclonal antibodies targeting TIGIT (T-cell immunoreceptor with Ig and ITIM domains) and their use in treating immune-related diseases including cancers and viral infections. Inventors: Jianhua Sui, Fang Yang, Linlin Zhao, Zhizhong Wei. The application includes 21 claims.
What changed
USPTO granted patent US12606619B2 to Huahui Health Ltd. on April 21, 2026. The patent covers human monoclonal antibodies against TIGIT (T-cell immunoreceptor with Ig and ITIM domains) and their use in treating immune-related diseases including cancers and viral infections. Inventors: Jianhua Sui, Fang Yang, Linlin Zhao, Zhizhong Wei.\n\nPharmaceutical and biotech companies developing checkpoint inhibitors or immuno-oncology therapies should review this patent for potential freedom-to-operate implications. The patent provides Huahui Health Ltd. with exclusive rights to the anti-TIGIT antibody platform for the specified therapeutic applications.
Archived snapshot
Apr 21, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Human monoclonal antibodies against TIGIT for immune related diseases
Grant US12606619B2 Kind: B2 Apr 21, 2026
Assignee
HUAHUI HEALTH LTD.
Inventors
Jianhua Sui, Fang Yang, Linlin Zhao, Zhizhong Wei
Abstract
The present invention relates to anti-TIGIT antibodies and antigen-binding fragments thereof that bind to both human TIGIT and mouse TIGIT. The present application also provides are nucleotides encoding the antibodies or fragments thereof, compositions or combinations comprising the antibodies or fragments thereof, and uses of the antibodies or fragments thereof in treatment of immune-related disease such as cancers and viral infection.
CPC Classifications
C07K 16/28 C07K 16/2803 C07K 16/2818 C07K 16/2827 C07K 2317/622 C07K 14/70503 C07K 2317/21 C07K 2317/56 C07K 2317/732 C07K 2317/734 C07K 2317/76 C07K 2317/92 A61P 35/00 A61K 2039/505 A61K 2039/507 A61K 2039/545 Y02A 50/30
Filing Date
2021-06-23
Application No.
18145309
Claims
21
Parties
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