AGC Inc Patent for Difluoromethylation Reaction Using Tetrafluoroethylene
Summary
The European Patent Office published patent application EP4385977A1, filed by AGC Inc., covering a difluoromethylation reaction of heterocyclic rings using tetrafluoroethylene. The inventors are NOMURA, Yoshitaka and SUZUKI, Haruya. The patent is classified under IPC codes C07D 215/12 and C07D 215/14, covering quinoline derivative synthesis methods. The application designates 31 European states including Germany, France, the United Kingdom, Italy, and Spain.
Chemical and pharmaceutical manufacturers researching fluorinated heterocyclic compounds should note this patent scope, as it may cover difluoromethylation processes using tetrafluoroethylene as a reagent. Companies developing generic quinoline-based pharmaceuticals or fluorine-substituted heterocyclic intermediates should conduct freedom-to-operate analysis before commercialising similar synthesis routes in Europe.
“DIFLUOROMETHYLATION REACTION OF HETEROCYCLIC RING USING TETRAFLUOROETHYLENE”
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GovPing monitors EPO Patent Bulletin - Organic Chemistry (C07D) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 63 changes logged to date.
What changed
The European Patent Office issued publication EP4385977A1, a granted European patent application for AGC Inc. covering a difluoromethylation reaction method for heterocyclic rings using tetrafluoroethylene as a reagent. The patent names NOMURA, Yoshitaka and SUZUKI, Haruya as inventors and is classified under IPC subclasses C07D 215/12 and C07D 215/14, indicating quinoline-based heterocyclic chemistry.
Companies in the chemical and pharmaceutical sectors that utilise tetrafluoroethylene in heterocyclic ring synthesis, or that produce difluoromethylated quinoline derivatives, should conduct a freedom-to-operate analysis for European markets. The 31 designated states (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR) mean the patent could affect commercialisation activities across the majority of European jurisdictions.
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Apr 25, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
DIFLUOROMETHYLATION REACTION OF HETEROCYCLIC RING USING TETRAFLUOROETHYLENE
Publication EP4385977A1 Kind: A1 Apr 15, 2026
Applicants
AGC INC.
Inventors
NOMURA, Yoshitaka, SUZUKI, Haruya
IPC Classifications
C07D 215/12 20060101AFI20250606BHEP C07D 215/14 20060101ALI20250606BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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