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Priority review Enforcement Amended Final

Fagron Compounding Services Recalls Norepinephrine Bitartrate Injection Due to Sterility and Component Issues

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Summary

FDA classified a Class II voluntary recall by Fagron Compounding Services for 25,260 bags of Norepinephrine Bitartrate Injection due to lack of assurance of sterility and a potential defect where the blue Break-Off-Part could detach from the administration port. The recall affects 14 lot numbers with expiration dates from April 23, 2026 through June 28, 2026 and was distributed nationwide in the United States. The firm initiated the recall on March 20, 2026.

Published by FDA on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

Fagron Compounding Services initiated a voluntary Class II recall affecting 14 lots of norepinephrine bitartrate injection totaling 25,260 bags. The recall was triggered by two product quality concerns: lack of assurance of sterility and a mechanical defect where the blue Break-Off-Part could detach from the administration port. FDA classified this as a Class II recall on April 7, 2026.\n\nHealthcare providers and facilities that received these lots should verify their inventory against the 14 affected lot numbers and suspend use pending further guidance. Pharmacies and clinical settings compounding or administering this product should quarantine affected stock and contact Fagron through the notification letter for return instructions.

Archived snapshot

Apr 20, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

Fagron Compounding Services

Drug Recalls (Class II)

← All Drug Recalls (Class II) Class II D-0438-2026 · 20260415 · Ongoing · Voluntary: Firm initiated

Product

norepinephrine Bitartrate,16mg per 250mL 0.9% Sodium Chloride Injection USP, Fagron Sterile Services, 8710 34th St. N. Wichita, KS 67226, NDC 71266-5026-02

Reason for Recall

Lack of Assurance of Sterility; blue Break-Off-Part could detach from the administration port

Affected Lot Numbers / Codes

Lot: C274-000049934, Exp.: 4/23/2026; C274-000049963, Exp.:4/24/2026; C274-000050074, Exp.: 4/30/2026; C274-000050123, Exp.:5/1/2026; C274-000050296, Exp.: 5/9/2026; C274-000050420, Exp.: 5/16/2026; C274-000050774, Exp.:6/5/2026; C274-000050924, 6/7/2026; C274-000050961, Exp.: 6/11/2026; C274-000050991, Exp.: 6/12/2026; C274-000051139, Exp.:6/19/2026; C274-000051166, Exp.:6/20/2026; C274-000051198, Exp.:6/21/2026; C274-000051343, Exp.:6/28/2026.

Quantity

25,260 bags

Firm Notification Method

Letter

Distribution

Nationwide in the U.S.A.

Initiated

20260320

FDA Classified

20260407

Sources: openFDA · Raw JSON

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Last updated

Classification

Agency
FDA
Filed
March 20th, 2026
Instrument
Enforcement
Branch
Executive
Legal weight
Binding
Stage
Final
Change scope
Substantive
Document ID
D-0438-2026

Who this affects

Applies to
Pharmaceutical companies Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Sterile compounding IV drug administration Drug recall response
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Clinical Operations
Compliance frameworks
GxP
Topics
Medical Devices

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