US Signs Health MOUs with Honduras and Senegal
Summary
The U.S. Department of State announced the signing of two bilateral health cooperation Memoranda of Understanding (MOUs) with Honduras and Senegal. These agreements represent significant investments in global health security, infectious disease preparedness, and local healthcare system strengthening, totaling over $136 million in combined U.S. and host country contributions.
What changed
The U.S. Department of State has executed two five-year Memoranda of Understanding (MOUs) for health cooperation with Honduras and Senegal, aligning with the Trump Administration's America First Global Health Strategy. The MOU with Honduras involves a $46.5 million investment ($29.6 million U.S., $16.9 million Honduran) focused on HIV/AIDS transition, infectious disease preparedness, and local capacity building, aiming for Honduras to detect outbreaks within seven days by 2030. The MOU with Senegal totals $90.4 million ($63.1 million U.S., $27.3 million Senegalese) to combat HIV and malaria, enhance health governance, upgrade facilities, and advance digital health systems, with a goal of Senegal producing 30% of its medicines locally.
These agreements signify a substantial commitment to global health security and international partnerships, with specific targets for disease detection, response times, and local healthcare worker integration. Regulated entities involved in global health initiatives or supplying medical technologies may see increased opportunities or shifts in partnership dynamics. While these are bilateral agreements, the scale of investment and strategic focus on preparedness and local capacity building highlight a trend in U.S. foreign health policy that compliance officers should monitor for potential implications on international operations and reporting requirements.
What to do next
- Review the terms of the MOUs with Honduras and Senegal for potential impact on existing or future international health programs.
- Assess opportunities for U.S. technology and service providers in the specified areas of health cooperation.
- Monitor future announcements regarding the implementation of these health partnerships and any related funding opportunities.
Source document (simplified)
Home Office of the Spokesperson Press Releases … Forging Health Partnerships Under the Trump Administration’s America First Global Health Strategy in Honduras and Senegal hide
Forging Health Partnerships Under the Trump Administration’s America First Global Health Strategy in Honduras and Senegal
Press Statement
Thomas "Tommy" Pigott, Principal Deputy Spokesperson
March 13, 2026
The United States signed bilateral health cooperation Memoranda of Understanding (MOUs) with the Republic of Honduras and the Republic of Senegal, marking significant milestones in advancing the Trump Administration’s America First Global Health Strategy while strengthening our partnerships in the Western Hemisphere and Africa.
In Honduras, the Department of State signed a five-year, $46.5 million bilateral health MOU which includes $29.6 million in U.S. investment and $16.9 million in Honduran co-investment—of which $9.6 million is dedicated to Global Health Security. The MOU integrates the transition of HIV/AIDS programming with strengthened infectious disease outbreak preparedness, with the goal of enabling Honduras to detect outbreaks within seven days, notify the United States within one day, and initiate a response within seven days by 2030.
Strategic investments will support laboratory capacity, epidemiological surveillance, supply chain modernization, the National Referral and Response System (SINARR), and the introduction of innovative American technologies such as lenacapavir. Honduras will also decrease dependency on U.S. foreign assistance by absorbing 95 U.S.-funded frontline healthcare workers and 14 laboratory staff into its own payroll by 2028, while gradually assuming procurement of HIV-related commodities and laboratory supplies.
In Senegal, the Department of State signed a five-year health cooperation MOU totaling $90.4 million. The Department of State, working with Congress, intends to provide $63.1 million to fight HIV and malaria, support health governance, laboratory capacity, health facility upgrades, and digital health systems advancement. Senegal commits to invest $27.3 million in co-financing. Senegal’s strategic objectives prioritize expanding health coverage, strengthening governance through quality control and establishing a new National Institute of Public Health, advancing digital health transformation with electronic patient records and telemedicine, and achieving pharmaceutical sovereignty by producing 30 percent of medicines locally using government of Senegal funds.
The MOU also includes $15.7 million in global health security funding to improve health governance, enhance laboratory capacity, upgrade health facilities, and advance digital health systems—critical investments that will strengthen Senegal’s ability to detect and respond to infectious disease outbreaks that could threaten both Senegalese and American populations.
America First Global Health Strategy Memoranda of Understanding (MOUs) signed so far represent more than $20.4 billion in new health funding including more than $12.6 billion in U.S. assistance alongside $7.7 billion in co-investment from recipient countries, building on decades of progress fighting HIV/AIDS, malaria, tuberculosis, and other infectious diseases around the world. As of March 13, the State Department has signed 26 bilateral global health MOUs with Botswana, Burkina Faso, Burundi, Cameroon, Côte d’Ivoire, the Democratic Republic of the Congo, the Dominican Republic, El Salvador, Eswatini, Ethiopia, Guatemala, Guinea, Honduras, Kenya, Lesotho, Liberia, Madagascar, Malawi, Mozambique, Niger, Nigeria, Panama, Rwanda, Senegal, Sierra Leone, and Uganda.
Tags
Bilateral Relations and Engagement Bureau of African Affairs Bureau of Global Health Security and Diplomacy Bureau of Western Hemisphere Affairs Disease Prevention, Detection, and Response Health Security Healthcare, Health Infrastructure, and Health Workers Honduras Office of the Spokesperson Senegal
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