Phthalic Anhydride Systematic Review (73 Pages)

EPA has released a systematic review document for phthalic anhydride, applying systematic review methods consistent with the Agency's TSCA risk evaluation process. The 73-page document synthesizes available scientific literature on the chemical's hazards, uses, and exposure pathways. \n\nAffected parties—including chemical manufacturers, importers, and downstream users of phthalic anhydride in plastics, resins, dyes, and related applications—should review this document and submit comments to inform EPA's assessment. The systematic review will likely form the scientific foundation for any subsequent risk evaluation or regulatory determination under TSCA, which could impose obligations on parties handling this substance.