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Priority review Enforcement Added Final

Apotex Brimonidine/Timolol Ophthalmic Solution Class II Recall

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Filed March 25th, 2026
Detected April 7th, 2026
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Summary

The FDA announced a Class II recall of Brimonidine Tartrate/Timolol Maleate Ophthalmic Solution 0.2%/0.5% manufactured by Apotex Corp. The recall (Case No. D-0407-2026) was initiated due to lack of assurance of sterility. The affected product has NDC 60505-0589-1 and was distributed nationwide in the U.S.

What changed

Apotex Corp. initiated a Class II drug recall (D-0407-2026) for Brimonidine Tartrate/Timolol Maleate Ophthalmic Solution 0.2%/0.5%, 5 mL (NDC 60505-0589-1) due to lack of assurance of sterility. The recall affects product manufactured at the Apotex facility in Weston, FL and distributed nationwide in the U.S.\n\nHealthcare providers should identify any patients who received this medication and advise them to return the product. Pharmacies should check their inventory for the affected NDC and quarantine any remaining stock. Adverse events possibly associated with this product should be reported to FDA MedWatch.

What to do next

  1. Identify affected product by NDC 60505-0589-1 and quarantine remaining inventory
  2. Notify patients who received this ophthalmic solution and advise them to return the product
  3. Report any adverse events possibly associated with this recalled product to FDA MedWatch

Source document (simplified)

Apotex Corp.

Drug Recalls (Class II)

← All Drug Recalls (Class II) Class II D-0407-2026 · 20260325 · Ongoing

Product

Brimonidine Tartrate/Timolol Maleate Ophthalmic Solution 0.2%/0.5%*, 5 mL, Rx Only, Sterile, Apotex Corp. Manufactured for: Apotex Corp., Weston, FL 33326, NDC 60505-0589-1.

Reason for Recall

Lack of Assurance of Sterility

Distribution

U.S. Nationwide

Source: openFDA Enforcement API

Named provisions

Product Reason for Recall Distribution

Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
FDA
Filed
March 25th, 2026
Instrument
Enforcement
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
D-0407-2026

Who this affects

Applies to
Drug manufacturers Healthcare providers Patients
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Manufacturing Sterile Product Quality Control
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Compliance
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Product Safety Healthcare

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