Viatris Healthcare Limited has informed healthcare professionals of a serious quality defect affecting Arixtra pre-filled syringes. The defect involves brown discoloration and blockage in the needle, caused by an extraneous iron particle that has oxidized. This issue necessitates immediate action to prevent administration of potentially compromised medication.

Healthcare providers are instructed not to dispense or administer Arixtra if the needle base in the pre-filled syringe shows discoloration. This direct healthcare professional communication highlights the critical need for vigilance in product inspection and administration to ensure patient safety and prevent adverse events related to the defective needles.