Biotech / Gene Therapy
EPO Patent Bulletin
160 items
(filtered)Reagents For Expanding Cells Expressing Recombinant Receptors
Rna Constructs And Uses Thereof
Nucleic Acid Polypeptide Compositions And Methods Of Inducing Exon Skipping
Detergent Composition Comprising Subtilase Variants
Alpha Crystalline Domain Proteins And Their Use In Genome Modification
Synthetic Helper Genes For Enhancing Viral Production
Compositions And Methods For Purifying Lentivirus Particles
Therapeutic Crispr/Cas9 Gene Editing Approaches To The C9 Orf72 Repeat Expansion Mutation In Ipscs
Engineered Rna Polymerase Variants
Treatment Of Samples Containing Nucleic Acids
Therapy For Alpha 1 Antitrypsin Deficiency
Compact Proteins
Hybrid Transient Transfection Using Transposase For High Yield Product Production
Metabolic Target For Therapy Of Chronic Vascular Inflammation
Compositions And Methods For Engineering T Cells For Improved Tumor Infiltration And Uses Thereof
Extracellular Vesicle Compositions And Preparation
Intra Striatal Co Transplantation Of Autologous Treg And Mda Cells In Parkinson's Disease Cell Therapy
Genetic Markers Associated With Increased Fertility In Maize
Rnai Targeting Kif1 A Missense Mutations For Treatment Of Kif1 A Associated Neurological Disorder
Compositions & Methods For Unlinked Architect Oligo Mediated Dna Synthesis
Systems And Method For Producing T Cells
Systems And Methods For Transposing Cargo Nucleotide Sequences
Compositions Comprising And Methods Of Using Dendritic Cell Exosomes
Lipids And Lipid Like Compounds For Therapeutic Lipid Nanoparticle (Lnp) Delivery
A Method For Precision Gene Therapy Of Diseases Caused By Endothelial Dysfunction
Vaccine Adjuvants
Optimized Antisense Sequences That Enhance Targeted Rna Editing By Adar Proteins
Compositions For Cell Specificsnca
Crispr Systems Targeting The Braf Gene Relating To The Treatment Of Melanoma
Engineered Recombinant Retroviruses
Vsv Based Sars Cov 2 Vaccine Candidates And Igy Antibodies As Prophylactic And Therapeutic Agents Against Sars Cov 2 And Variants Of Concern
A Host Cell With Increased Cellular Reducing Power From A Heterologous Hydrogenase
Continuous Polyhydroxyalkanoate Production By Perchlorate Respiring Microorganisms
Aav Mediated Gene Therapy
Nuclease Guided Non Ltr Retrotransposons And Uses Thereof
Compositions And Methods For Genome Editing
Transient Modified Rna Based Elevated Expression Of Fli 1 To Augment Hematopoietic Stem And Progenitor Cell Expansion
Mutant Dna Polymerases And Methods Of Use
A Method To Produce Crystalline Lactose Produced By A Biotechnological Production Process
Single Stranded Loop Oligonucleotides
Antisense Long Noncoding Rnas For The Modification Of Gene Expression And For Therapeutic Applications
Compositions And Methods For Recombinant Aav Production
Compositions, Methods And Uses Of Messenger Rna
Non Human Animals Comprising A Humanized Asgr1 Locus
Mice Expressing A Limited Immunoglobulin Light Chain Repertoire
Composition And Methods Of Genome Editing Of B Cells
Protease Variants And Detergent Compositions Comprising Same
Multiplexed Genome Editing
Determining Antigen Recognition Through Barcoding Of Mhc Multimers
Pharmaceutical Composition Comprising Ccn5 As Active Ingredient For Preventing Or Treating Retinal Disease
Novel Lactic Acid Bacteria And Use Thereof
Rnai Agents For Hepatitis B Virus Infection
Variants Of Cpf1 (Cas12 A) With Altered Pam Specificity
Method For Producing Cd3 Positive Cell
Method, Device And System For Electroporation Of Biological Cells In A Fluidic Channel
Multiplexed Target Binding Candidate Screening Analysis
Methods And Compositions For Increasing Arylsulfatase A Activity In The Cns
Grass Endophytes
Kit, Device, And Method For Detecting Lung Cancer
Methods For Treatment Using Adoptive Cell Therapy
Novel Carbonyl Lipids And Lipid Nanoparticle Formulations For Delivery Of Nucleic Acids
Type V Crispr Cas Base Editors And Methods Of Use Thereof
Rna Interference Delivery Formulation And Methods For Malignant Tumors
Use Of Tumor Infiltrating Lymphocytes For Treating Nsclc Patients Refractory For Anti Pd 1 Antibody
Cas Variants For Gene Editing
Methods And Compositions For Treating Cancers Using Antisense
Chemiluminescent Wetness Indicator For Absorbent Products
Aptamer Sirna Fusions
Chimeric Antigen Receptor (Car) T Cells And Uses Thereof
Retrotransposon Compositions And Methods Of Use
Targeted Treatment Of Spliceopathy Induced Neurological Disorders
Methods For Actively Loading Therapeutic Nucleic Acid Molecules Into Modified Extracellular Vesicles For The Targeted Cell Delivery
Retrotransposon Compositions And Methods Of Use
System And Apparatus For The Hand Held Amplification And Detection Of Nucleic Acids
Fungal Compositions And Methods Of Use Thereof
Uricase Conjugates And Methods Of Use Thereof
Immobilized Enzymes For Bioelectrocatalysis
Porphyria Disease Models
Pbase Protein, Fusion Protein, Nucleic Acid, Gene Integration System And Use
Increasing Gene Editing And Site Directed Integration Events Utilizing Developmental Promoters
Microbial Consortia For Soil Improvement
Methods Of Selecting And Treating Cancer Subjects That Are Candidates For Treatment Using Inhibitors Of Parp
Multiplex Gene Edited Cells For Cd70 Directed Cancer Immunotherapy
Compositions And Methods For Improved Protein Translation From Recombinant Circular Rnas
Vectors Combining Anti Sickling Beta As3 Globin With Anti Bcel11 A Sh Rna Mir To Treat Beta Hemoglobinopathies
Lysine Free Ubiquibody Variants For Long Lived Intracellular Protein Silencing
Adeno Associated Viral Vector For Glut1 Expression And Uses Thereof
Mrna Expression And Delivery Systems
Methods For Generating Biologically Specific Chromatin Condensates And Uses Thereof
Cyanobacteria Cultivation, Sedimentation, And Utilization
Production Of Rna Polynucleotides Encoding Picornavirus
Tdt Specific Chimeric Receptors And Methods Of Their Use
Purification Process
Hypoimmune Beta Cells Differentiated From Pluripotent Stem Cells And Related Uses And Methods
Expression Cassettes For Treating Epilepsy And Neuropathic Pain
Compositions, Devices And Methods For Treating Cns Disorders
Allogeneic T Cells For Treatment Of Hematological Malignancies
Biointerface Layer For Analyte Sensors
Varietal Counting Of Nucleic Acids For Obtaining Genomic Copy Number Information
Use Of The Cd2 Signaling Domain In Second Generation Chimeric Antigen Receptors
Initiating Capped Oligonucleotide Primers For Synthesizing 5' Capped Rnas
Cell Free Production Of Ribonucleic Acid
Methods For Increasing The Efficiency Of Homology Directed Repair (Hdr) In The Cellular Genome
Novel Crispr Dna Targeting Enzymes And Systems
Novel, Non Naturally Occurring Crispr Cas Nucleases For Genome Editing
Menotropin For Treating Infertility
Novel Crispr Dna And Rna Targeting Enzymes And Systems
Compound For Use In Methods For Treatment Of Polycystic Kidney Disease
Differentiation And Use Of Human Microglia Like Cells From Pluripotent Stem Cells And Hematopoietic Progenitors
Peptide Having Effects Of Increasing Telomerase Activity And Extending Telomere, And Composition Containing Same
Process For The Preparation Of Erythrocytes Loaded With One Or More Substances Of Pharmaceutical Interest And So Obtained Erythrocytes
Culture Medium For Epithelial Stem Cells And Organoids Comprising Said Stem Cells
Inducible Coexpression System
Identification Of Common Tumor Specific T Cell Receptors And Antigens
Biocementation Method And System
Artificial Nucleic Acid Molecules For Improved Protein Expression
Automated Method And Apparatus For Preparing Bioprocess Solutions
Methods Of Altering Gene Expression By Perturbing Transcription Factor Multimers That Structure Regulatory Loops
Methods Of Polynucleotide Synthesis
Pseudotyped Viral Particles, Compositions Comprising The Same, And Uses Thereof
Methods For The Reduction Of Methane Production In Ruminants
Methods For Making Extracellular Vesicles, And Compositions And Methods Of Use Thereof
Retargeted Retroviral Vectors Resistant To Vaccine Induced Neutralization And Compositions Or Methods Of Use Thereof
Relaxin 2 Fusion Protein Analogs And Methods Of Using Same
Cellular Engineering To Improve Cannabinoid Production In Microbial Cells
Recombinant Newcastle Disease Virus Expressing Spike Protein Of Sars Cov 2 Delta Variant And Uses Thereof
Generating Northern Leaf Blight Resistant Maize
Methods For The Production Of Tryptophans, Tryptamines, Intermediates, Side Products And Derivatives
Engineering B Cell Based Protein Factories To Treat Serious Diseases
Epigenetic Gene Regulation To Treat Neurological Diseases And Pain
Platelet Alpha Granules For Delivery Of Multiple Proteins
Aav8 Capsid Variants With Enhanced Liver Targeting
Microbial Oil And Method For Producing Microbial Oil
Cell Controlled Perfusion In Continuous Culture
Products And Compositions
Engineered Crispr Cas Systems And Methods For Sensitive And Specific Diagnostics
Recombinant Sars Cov 2 Spike Protein Subunits, Expression And Uses Thereof
Methods And Compositions For Modulating A Genome
Systems, Methods, And Compositions For Rna Guided Rna Targeting Crispr Effectors
Regioselective Oxidation Of Heterocyclic Alpha Amino Amides
Lymphocytes Expressing Heterologous Targeting Constructs
Lung Cancer Detection Kit Or Device, And Detection Method
Microorganisms And Methods For The Fermentation Of Cannabinoids
Chimeric Proteins For Selective Lysis Of Bacteria
A Method Of Altering A Differentiation Status Of A Cell
A Cell Based Method For Determining An Activity Of Botulinum Toxin
Methods For Expansion Of Natural Killer (Nk) Cell Subset And Related Compositions And Methods
Methods And Compositions For Preparing Nucleic Acids That Preserve Spatial Proximal Contiguity Information
Mycobacterial Antigen Compositions And Methods Of Use
Method For Increasing Secretion Of Recombinant Protein
Bacterium Constitutively Producing Monophosphoryl Lipid A And Method Of Producing Monophosphoryl Lipid A By Using Bacterium
Compositions And Methods For Treating Pain Disorders
Compositions And Methods For Treating Phenylketonuria
Compositions For The Treatment Of Disease
Three Dimensional Printed Organs, Devices, And Matrices
Methods For Adeno Associated Viral Vector Production
Methods For Producing Isobutene From 3 Methylcrotonic Acid
Sarna Compositions And Methods Of Use
Process For Culturing Microalgae Of The Genus Aurantiochytrium In A Culture Medium Without Sodium And Without Chloride For The Production Of Dha
Generation Of Neural Stem Cells From Human Trophoblast Stem Cells