Mesenchymal Stromal Cells as Reprogramming Source for iPSC Induction
Summary
The USPTO granted Patent US12590295B2 to The University of Hong Kong covering mesenchymal stromal cells as a reprogramming source for induced pluripotent stem cell (iPSC) induction. The patent, filed November 27, 2020, protects methods for generating induced mesenchymal stromal cells and their use in iPSC production. Entities conducting iPSC-related research or development should assess whether licensing is required.
What changed
The USPTO issued Patent US12590295B2 to The University of Hong Kong on March 31, 2026, granting exclusive rights to methods of using mesenchymal stromal cells as a reprogramming source for iPSC induction. The patent names five inventors including Chi-Fung Chan and Kenneth Richard Boheler, with CPC classifications in cellular therapy and stem cell technologies.
Biotechnology companies, pharmaceutical researchers, and academic institutions engaged in iPSC work should conduct freedom-to-operate analyses to determine if this patent covers their activities. Licensing negotiations may be necessary for commercial applications. No immediate compliance action is required, but this grant affects competitive positioning in the cell therapy and regenerative medicine space.
Archived snapshot
Mar 31, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Mesenchymal stromal cells as a reprogramming source for iPSC induction
Grant US12590295B2 Kind: B2 Mar 31, 2026
Assignee
The University of Hong Kong
Inventors
Chi-Fung Chan, Kenneth Richard Boheler, Jiangang Shen, Ruixia Deng, Hing Yee Law
Abstract
Provided are mesenchymal stromal cells as a reprogramming source for ipsc induction. In particular, Provided is a method for generating induced mesenchymal stromal cells (iMSCs), the iMSC generated by the method as well as the use thereof.
CPC Classifications
C12N 5/0668 C12N 2501/11 C12N 2501/115 A61K 35/28
Filing Date
2020-11-27
Application No.
17756711
Claims
1
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