Epoxytiglienone Compounds for Disrupting Gram-negative Bacterial Biofilms

Mon, 13 Apr 2026 13:40:19 +0000
Pharmaceuticals

The USPTO has published patent application US20260097011A1 for epoxytiglienone compounds designed to disrupt biofilms comprising Gram-negative bacteria. The application covers methods of dispersing established biofilms through localized administration, including topical or injection delivery, as well as methods for preventing biofilm formation on medical devices. Inventors include David William Thomas, Paul Warren Reddell, Glen Mathew Boyle, and others. The application was filed on December 2, 2025.