← USPTO Patent Grants

Antisense oligonucleotide-based progranulin augmentation therapy in neurodegenerative diseases

Grant US12595479B2 Kind: B2 Apr 07, 2026

Assignee

PRESIDENT AND FELLOWS OF HARVARD COLLEGE

Inventors

Peter Jungsoo Park, Jin Kuk Kim, Timothy Yu, Yu-Han Huang

Abstract

Described herein are methods and compositions related to the modulation of progranulin expression or activity in the brain for the treatment of neurodegenerative diseases.

CPC Classifications

C12N 15/113 C12N 2310/11

Filing Date

2020-03-19

Application No.

17440438

Claims

11