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CD133-binding agents and uses thereof

Grant US12595312B2 Kind: B2 Apr 07, 2026

Assignee

The Governing Council of the University of Toronto

Inventors

Jason Moffat, Jarrett Adams, Guohua Pan, Sachdev Sidhu, Rashida Williams, Xiaoyu Zhang, Sheila K. Singh, Parvez Vora, Chitra Venugopal

Abstract

This disclosure is directed to novel CD133-binding agents. The disclosure is also directed to uses of novel CD133-binding agents for detecting CD133-expressing cells and/or quantitating levels of cellular CD133 expression, for targeting CD133-expressing cells, for decreasing levels of CD133 in CD133-expressing cells and for treating or preventing cancer.

CPC Classifications

A61K 2039/505

Filing Date

2021-10-26

Application No.

17511420

Claims

27