Compositions and methods for treatment of thyroid eye disease
Grant
US12595309B2
Kind: B2
Apr 07, 2026
Assignee
Viridian Therapeutics, Inc.
Inventors
Vahe Bedian, Peter Harwin, Tomas Kiselak, Angela She, Jonathan Violin, Yang Zhao
Abstract
Antibodies and compositions against Insulin-Like Growth Factor-1 Receptor (IGF-1R) and uses thereof are provided herein and antibodies and pharmaceutical compositions that can be used in methods of treating or reducing the severity of thyroid eye disease (TED) in subjects in need thereof, including reducing proptosis and Clinical Activity Score (CAS), by inhibiting the activity of IGF-1R with such antibodies and compositions.
CPC Classifications
C07K 16/2863
A61P 27/02
Filing Date
2024-11-08
Application No.
18942051
Claims
23