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TREM2 stabilizing antibodies

Grant US12595305B2 Kind: B2 Apr 07, 2026

Assignee

Novartis AG

Inventors

Verena Brand, Dominik Feuerbach, Fabrizio Gasparini, Nathalie George, Eveline Schaadt, Derya Shimshek, Honnappa Srinivas, Markus Waldhuber, Rainer Wilcken

Abstract

The present invention provides antibodies that bind to and stabilize human Triggering Receptor Expressed on Myeloid cells 2 (TREM2) protein and methods of using these antibodies.

CPC Classifications

C07K 16/2803 C07K 2317/565 C12N 15/70

Filing Date

2022-09-23

Application No.

17934795

Claims

10