Methods to decrease impurities from recombinant protein manufacturing processes
Grant
US12595294B2
Kind: B2
Apr 07, 2026
Assignee
Hoffmann-La Roche Inc.
Inventors
Marc Pompiati, Christoph Feistl
Abstract
The invention relates to a method of reducing the amount of non-aggregate produce-related impurities (NAPRIs) in a buffered solution of monoclonal antibodies (mAbs), involving the use of a synthetic depth filter. The invention may be of use in the purification of monoclonal 5 antibodies.
CPC Classifications
C07K 16/065
Filing Date
2022-07-12
Application No.
17812145
Claims
15