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Morpholine-like monoamine releasers

Grant US12595269B2 Kind: B2 Apr 07, 2026

Assignee

Solvonis Therapeutics Ireland Holdings Limited

Inventors

Alan Borthwick, Fabrizio Micheli, Alessandra Micoli, Ferruccio Palazzesi, Agostino Cianciulli, Robin Tyacke, David Nutt

Abstract

Disclosed herein are certain therapeutic substituted heterocyclic bridged ring compounds, including substituted morpholine, thiomorpholine, and piperidine compounds and their homologues, having various advantages over current compounds used in certain methods of drug-assisted therapy, such as MDMA, together with pharmaceutical compositions containing such compounds, and methods of their use to treat mental health disorders and CNS disorders.

CPC Classifications

A61K 31/407

Filing Date

2023-02-16

Application No.

18838986

Claims

20