Preparation method for amide compound and application thereof in field of medicine
Grant
US12595267B2
Kind: B2
Apr 07, 2026
Assignee
SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO., LTD.
Inventors
Xin Xu, Jia Chen, Zhen Zhang, Liming Zhang, Qimei Wu, Qingyun Jiang, Fengying Guo, Yuyun Zhang, Hao Yu, Ying Wang, Kang Sun, Chengxu Zang, Chenggang Qin, Xiaobo Zhou, Xiaojuan Zhang, Yijin Wang, Xiaoer Xia, Yunfei Li, Jian Ge
Abstract
The present invention relates to a preparation method for an amide compound and an application thereof in the field of medicine. Specifically, provided by the present invention is an amide small molecule compound which is an inhibitor of Zeste gene enhancer homolog 2 (EZH2) and which may be used to prevent and/or treat EZH2-mediated related diseases, comprising tumors, myeloproliferative diseases or autoimmune diseases.
CPC Classifications
C07D 491/107
C07D 405/12
C07D 405/14
C07D 487/04
A61P 35/00
Filing Date
2020-03-24
Application No.
17442899
Claims
11