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Small molecule inhibitors of mammalian SLC6A19 function

Grant US12595244B2 Kind: B2 Apr 07, 2026

Assignee

Jnana Therapeutics Inc.

Inventors

Dean G. Brown, Giovanni Muncipinto, Joshua Ethan Zweig, Long Vo Nguyen

Abstract

Disclosed are compounds, compositions, and methods useful for treating or preventing a disease or disorder associated with abnormal levels of amino acids by modulation of SLC6A19 transport.

CPC Classifications

A61K 31/4523 A61K 31/4525 A61K 31/453 A61K 31/4535 A61K 31/454 A61K 31/4545 A61K 31/497 A61K 31/501 A61K 31/506 A61K 31/5377 C07D 211/58 C07D 401/06 C07D 401/04 C07D 401/14 C07D 403/04 C07D 405/06 C07D 405/14 C07D 409/06 C07D 409/14 C07D 413/04 C07D 413/06 C07D 413/12 C07D 413/14 C07D 417/04 C07D 417/06 C07D 417/14 C07D 471/04 C07D 487/04

Filing Date

2025-05-30

Application No.

19224188

Claims

2