Production of exosomes and uses thereof
Grant
US12594344B2
Kind: B2
Apr 07, 2026
Assignee
China Medical University
Inventors
Yi-Wen Chen, Der-Yang Cho, Hsin-Yuan Fang, Ming-You Shie, Chih-Ming Pan, Kai-Wen Kan, Cheng-Yu Chen, Min-Hua Yu, Shao-Chih Chiu
Abstract
A method for producing exosomes in a large-scale by using a cyclic tensile bioreactor to stimulate cells to release exosomes. In addition, the exosome having an anti-HLA-G protein specific for cancer is used as a delivery vehicle to deliver therapeutic agents for treating cancer.
CPC Classifications
A61K 47/6901
A61P 35/00
C07K 14/70596
C07K 16/2833
C07K 2317/569
C07K 2319/03
C12N 5/0686
C12N 2527/00
Filing Date
2022-12-02
Application No.
18060966
Claims
10