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Single domain antibodies and their use in cancer therapies

Grant US12594302B2 Kind: B2 Apr 07, 2026

Assignee

Institut Curie

Inventors

Sandrine Moutel, Franck Perez, Michele Bernasconi, Nagjie Laila Alijaj, Zélia Gouveia

Abstract

The present application relates to fully humanized anti-FGFR4 single domain antibodies (sdAbs) and variants thereof. The present invention further relates to functionalized drug nanocarriers, nucleic acids, vectors, host cells, immune cells comprising said sdAbs, and compositions comprising thereof, as well as their use for therapy.

CPC Classifications

C07K 16/2863 A61K 40/31

Filing Date

2021-05-20

Application No.

17925411

Claims

24