CBL inhibitors and compositions for expansion of immune cells
Grant
US12594263B2
Kind: B2
Apr 07, 2026
Assignee
NURIX THERAPEUTICS, INC.
Inventors
Jennifa Gosling, Arthur T. Sands, Sarah Anne Whelan, Michael Lotze
Abstract
Methods and compositions using novel Cbl inhibitors enhancing expansion of immune cells to increase the efficacy of cell-based immunotherapeutics are disclosed. Also provided are cell-based immunotherapy methods and compositions.
CPC Classifications
A61K 35/17
A61K 31/4196
A61K 31/454
A61K 31/4545
A61K 31/506
A61K 31/5377
A61K 31/713
A61K 31/5375
A61K 45/06
A61K 38/20
A61K 38/2013
A61K 38/2086
A61K 38/217
A61K 38/2046
A61K 2300/00
A61P 35/00
A61P 37/04
C12N 5/0636
C12N 2501/2302
C12N 2501/2307
C12N 2501/2315
C12N 2501/2321
C12N 2501/72
C12N 2506/11
Filing Date
2020-09-23
Application No.
17030258
Claims
31