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Methods and compositions for treating inflammatory conditions associated with infectious disease

Grant US12590310B2 Kind: B2 Mar 31, 2026

Assignee

DIRECT BIOLOGICS, LLC

Inventors

Kenneth Allen Pettine, Kevin Hicok, Timothy Alexander Moseley

Abstract

Disclosed are methods of treating perianal fistula a subject by administering a therapeutic MSC secretome product made by a method comprising culturing bone marrow-derived MSCs under conditions that include oxygen tension below 5% and a culture media with a pH below 7.

CPC Classifications

A61K 9/127 A61K 38/1709 A61K 38/177 A61K 45/06

Filing Date

2021-04-22

Application No.

17920997

Claims

18