← USPTO Patent Grants

Translation enhancing nucleic acid compounds: ASO coupled translation-upregulation 1 (ACT-UP1) and uses thereof

Grant US12590307B2 Kind: B2 Mar 31, 2026

Assignee

ARNATAR THERAPEUTICS, INC

Inventors

Xuehai Liang, Lingdi Zhang

Abstract

Disclosed herein are methods and compounds for enhancing gene expression by ACT-UP1 compounds. Such methods and compounds are useful for increasing expression of certain genes, many of which are associated with a variety of diseases and disorders.

CPC Classifications

C12N 15/113 C12N 15/67 C12N 2310/11 C12N 2310/315 C12N 2310/321 C12N 2310/322 C12N 2310/3231 C12N 2310/3341 C12N 2310/3519 A61K 9/0019 A61K 38/1709 A61P 1/16

Filing Date

2025-02-14

Application No.

19054728

Claims

21