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Combination therapies against cancer targeting CD38 and TGF-β

Grant US12590167B2 Kind: B2 Mar 31, 2026

Assignee

Sanofi

Inventors

Francisco Adrian, Richard C. Gregory, Gary Shapiro, Helgi Van De Velde

Abstract

The present disclosure relates to combination cancer therapies targeting CD38 and TGF-β using antibodies specific for these targets. Also provided are compositions useful in the therapies.

CPC Classifications

C07K 16/2896 C07K 16/22 C07K 2317/565 C07K 2317/732 C07K 2317/76 A61K 31/12 A61K 2039/507 A61K 31/573 A61P 35/00

Filing Date

2019-07-10

Application No.

17259135

Claims

11