Antibodies binding to citrullinated histone 2A and/or 4
Grant
US12590143B2
Kind: B2
Mar 31, 2026
Assignee
Citryll B.V.
Inventors
Jozef Maria Hendrik Raats, Renato Gerardus Silvano Chirivi, Johannes Wilhelmus Gerardus Van Rosmalen
Abstract
The invention provides antibodies or binding fragments thereof directed against citrulline-containing epitopes. The antibodies or binding fragments thereof of the invention can be used in therapy, for example in the treatment or prevention of Neutrophil Extracellular Trap (NET)-associated pathologies.
CPC Classifications
C07K 16/18
C07K 2317/24
C07K 2317/565
A61P 19/02
A61P 29/00
A61K 2039/505
Filing Date
2022-05-27
Application No.
17827488
Claims
13